Diabetic Neuropathy and Sexual Dysfunction

Sexual dysfunction commonly develops in people who have diabetic autonomic neuropathy. That’s because diabetic neuropathy affects the para­sympathetic fibers that regulate erections in men and vaginal lubrication in women. It also affects the sympathetic nervous system, which mediates orgasm and ejaculation.

Sexual Dysfunction In Men

Men with autonomic neuropathy may experience retrograde ejaculation (semen ejaculation into the urinary bladder) or impotence. Retrograde ejaculation results from damage to the efferent sympathetic nerves. These nerves normally coordinate the simultaneous closure of the internal vesicle sphincter and relaxation of the external vesicle sphincter during ejaculation. Signs and symptoms of retrograde ejaculation include cloudy urine after intercourse, infertility, and a decreased volume of ejaculate.

If your patient has incomplete retrograde ejaculation or the problem has recently been diagnosed, the physician may advise him to have intercourse when his bladder is distended. Other therapeutic options include taking an antihistamine or desipramine to restore ejaculation.

A patient who’s impotent can’t attain or maintain an erection despite having a normal sex drive. When evaluating whether impotence results from autonomic neuropathy, the physician will consider other possible causes, such as drugs, alcohol use, hormonal deficiencies, and psychological problems. The physician may evaluate the patient’s serum hormone levels and penile blood flow and pressure measurements to help make the diagnosis, or the physician may refer the patient to a urologist for further evaluation.

Diabetic Neuropathy and Sexual DysfunctionBecause a patient with impotence may be hesitant to discuss his sexual concerns, you may have to bring up the subject yourself. For instance, you can say, “Many of my patients who have diabetes complain of impotence. Has this been a problem for you?” If he acknowledges the problem, explore it with him. Ask if anything seems to make the problem better. If he’s uncomfortable talking with you, give him an educational pamphlet or suggest that he discuss it with the physician.

Explain to your patient that effective and acceptable treatments are available. For example, vacuum devices can be used to draw blood into the penis to produce an erection. Or a rigid or semirigid penile prosthesis can be surgically implanted. The physician may also prescribe alprostadil, which the patient administers intracavernously shortly before sexual intercourse, or silenafil, which he takes orally 112 to 4 hours before sexual intercourse.

Sexual Dysfunction In Women

Women with diabetic autonomic neuropathy may experience difficulties with arousal, diminished vaginal lubrication, and anorgasmy despite a normal sex drive. Symptoms include dyspareunia (painful intercourse) and a delayed orgasm or none at all. If your patient is experiencing these symptoms, advise her to use a vaginal lubricant and to ask the physician for a referral to a gynecologist for further evaluation. Her gynecologist may prescribe an estrogen cream.

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Benifical Effects of Fiber

Water-insoluble fiber (which includes wheat, bran, and whole grain products) affects mainly the lower gastrointestinal (GI) tract, where it increases fecal bulk, helps to prevent constipation, and may reduce the risk of colon cancer. Water­soluble fiber (which includes guar and pectin) affects the upper GI tract by delaying gastric emptying and increasing the intestinal transport time. It may also lower levels of total cholesterol and LDL cholesterol.Although fiber’s beneficial effect on glucose level control remains unproved, eating 20 to 35 grams of water-insoluble or water-soluble fiber a day does promote evacuation and lower lipid levels. Instruct your patients who are increasing their fiber intake to do so gradually and to drink at least 8 cups of fluid a day to minimize GI discomfort.

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Diagnostic Tests of Diabetic Retinopathy

To diagnose diabetic retinopathy, an ophthalmologist uses an ophthalmoscopic examination or fluorescein angiography. During an ophthalmoscopic examination, the ophthalmologist dilates the patient’s eyes with a mydriatic drug, such as atropine. This dilation permits viewing of the retina, retinal blood vessels, optic disc, macula, and other structures.The ophthalmologist uses fluorescein angiography to evaluate leaking or occluded retinal vessels. In this outpatient procedure, fluorescein dye is injected into an arm vein. Then the dye travels through the blood to different parts of the body, including the retinal capillaries. By using fluorescein dye and a fundus camera with filters, the ophthalmologist can better see the retinal blood vessels and determine if the patient has retinopathy and, if so, to what extent.

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Diagnostic Tests of Peripheral Neuropathy

The physician usually diagnoses peripheral neuropathy by excluding other causes of your patient’s signs and symptoms. Typically, the physician will assess her neurologic function, evaluating her deep tendon reflexes and muscle strength and testing how well she senses temperature, light touch, sharp and dull sensations, vibration in her feet, and changes in the position of her toes.Temperature sensation in the feet and legs can be assessed by touching a cool metal object, such as a tuning fork, to the skin and asking your patient to describe the temperature. Light touch can be assessed by touching the skin with a wisp of cotton or a monofilament device and asking her to describe the location of the sensation. Sharp and dull sensation can be assessed by asking your patient to close her eyes and then alternately touching her feet with the dull and sharp ends of an object, such as a paper clip, and asking her to describe the sensation. Vibration sensation is assessed by placing a vibrating tuning fork on the distal first metatarsal head or the malleolus of your patient’s ankles and asking her to tell you when the vibration stops. To assess your patient’s position sense, ask her to close her eyes; then flex and extend her great toe and have her describe its position.

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How to Cope up with Sight Problems for Diabetic Patients

Before being diagnosed and eventually treated for their diabetes, some diabetics experience sight problems due to their disease. These problems may be blurry vision, difficulties to focus and sudden near- or farsightedness. These problems may also be present during the first months of treatment. This might cause unnecessary worry, but is something that occurs to many diabetics, and it is due to the high blood sugar levels, that affect the eyes’ lenses. It is important however that the patient, if he or she is already using contact lenses or glasses, doesn’t walk right away to the local eye care professional to try out new lenses to cure this unexpected problem. When the treatment sets in, and the blood sugar goes back to normal, so does the changes of the lenses, and the vision is very likely to become normal again.

Diabetes patients otherwise usually don’t have any trouble using contacts or glasses, since the disease rarely affect the eyes. Any type of contact lens, like soft lenses or extended-wear lenses, is not likely to cause any problems. It is important however to have regular contact with the eye care professional, to make sure that any eye problems will not return and become permanent.

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Serum Creatinine and Blood Urea Nitrogen Tests

One complication of diabetes is diabetic nephropathy. A quick and simple way to check renal function is to draw a blood sample for serum creatinine and BUN tests. These tests should be performed when the patient is diagnosed with diabetes.Although the serum creatinine and BUN tests can quickly reveal the patient’s renal function, serum creatinine is the more sensitive indicator. Many extrarenal conditions, such as dehydration, can elevate the BUN level, but serum creatinine changes little except in renal disease. A normal serum creatinine level for an adult ranges between 0.7 and 1.5 mgjdl (0.6 and 1.2 mg/dl for adults over age 65). A normal BUN level for an adult ranges between 4 and 22 mg/dl (8 and 18 mgjdl for adults over age 65). Elevations in your patient’s serum creatinine and BUN levels require further testing before a physician can make a diagnosis of diabetic nephropathy

Nursing Considerations

Test results are more accurate if your patient fasts for 8 hours beforehand; therefore, try to schedule the test for first thing in the morning, so that most of the fasting time will occur while she is sleeping. Tell her not to eat breakfast.

Serum Creatinine and Blood Urea Nitrogen TestsIf your patient is taking ascorbic acid, a barbiturate, or a diuretic, her physician will probably withhold it until after the test because these drugs can raise serum creatinine levels. Note whether your patient is receiving amphotericin B, an aminoglycoside, methicillin, or chloramphenicol. Any of these nephrotoxic drugs could be the source of her renal impairment.

After drawing the blood, send the sample to the laboratory immediately. To prevent hemolysis, which can alter the test results, handle the blood sample gently.

If the BUN level is elevated but the serum creatinine level isn’t, consider possible extrarenal causes before repeating the tests. Also, keep in mind that the amount of creatinine produced in the body is related to muscle mass. Therefore, an athlete with normal renal function may have elevated levels of serum creatinine.

If your patient’s serum creatinine and BUN levels are both high, check them frequently to monitor her renal function. Abnormal renal function coupled with diabetes places your patient at increased risk for endstage renal disease and cardiovascular disease. The frequency of these tests depends on how high the patient’s serum creatinine and BUN levels are and whether she exhibits other signs.

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Adaptations for Elderly Patients

A dietitian adapts a nutritional plan for an elderly patient with diabetes based on her special needs caused by aging. For instance, the poor vision that typically accompanies old age can affect a patient’s nutritional status by making it hard for her to read food labels or blood glucose meter results. Also, decreased mobility commonly affects a person’s ability to buy and prepare food. And declining mental status may make it difficult for your patient to plan and prepare meals or even remember to eat (or whether she has eaten).Adaptations for Elderly PatientsMany older people have limited finances, so they may not purchase a wide variety of fresh foods. They often eat irregularly, skipping meals or eating on a random schedule. A declining sense of taste and poor dentition affect nutrition by making mealtimes seem less pleasurable and more trouble than they’re worth. Other elderly people may have a chronic disease, such as kidney or cardiac disease, that increases the challenge of developing a nutritional plan.

Many elderly people take several drugs at the same time, increasing the risk of food-drug and drug-drug interactions, which may affect appetite, taste, and the ability to digest, absorb, metabolize, and excrete nutrients.

Meals delivered to a patient’s home may improve mealtime regularity and food variety. But as with meals served in long-term care facilities, home-delivered meals may limit the patient’s control over food choices and meal timing. A meal plan that concentrates on eating meals at the same time every day and eating foods that provide good nutrition may be the best way to overcome the obstacles faced by elderly patients.

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Dialysis of Diabetic Nephropathy or End Stage Renal Disease

If your patient develops end-stage renal disease, she may require hemodialysis or peritoneal dialysis to prolong her life. The physician probably won’t recommend dialysis until your patient’s serum creatinine level is about 6 mg/dl.

Hemodialysis

For hemodialysis, the surgeon creates an arteriovenous (AV) access site, usually in the patient’s arm, as shown. With each hemodialysis treatment, a needle is inserted into this AV access site. Blood is withdrawn through the arterial line and pumped through a semipermeable membrane in the hemodialysis machine. As the blood is pumped, dialysate moves through the membrane in the opposite direction, allowing body wastes to move by diffusion from an area of high concentration to an area of low concentration.

The pores in the membrane allow electrolytes, blood urea nitrogen, and creatinine to be filtered out, but they prevent larger particles such as blood cells and protein from passing through. The filtered blood is then returned to the patient through the venous line.

Hemodialysis can be performed in your patient’s home or in a medical facility. Treatments average 3 to 4 hours, three times each week.

Peritoneal Dialysis

Dialysis of Diabetic Nephropathy or End Stage Renal DiseaseIn this closed-drainage procedure, a catheter is placed through an opening in the abdominal wall. At regular intervals, dialysate is instilled into the peritoneal cavity. Through osmosis and diffusion, fluid, electrolytes, and waste products are drawn from the blood, across the peritoneum, and into the dialysate. The peritoneum, which lines the peritoneal cavity, acts as a semipermeable membrane. The dialysate is drained regularly and replaced.

Most patients tolerate peritoneal dialysis better than hemodialysis. The patient’s blood pressure usually remains stable, and she experiences less cardiovascular stress and better control of her blood glucose levels. She’ll also have a decreased risk of retinal hemorrhage because she won’t need the higher doses of heparin that are used with hemodialysis. However, peritoneal dialysis places the patient at higher risk for developing an infection, such as peritonitis.

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Immunosuppressive Drugs

Usually, transplant patients take immunosuppressive drugs to prevent the transplanted organ from being rejected over the long term or to treat incipient rejection. They may start to take these drugs before surgery and continue throughout the life of the organ. Methylprednisolone and azathioprine are usually administered I.V. during surgery. As kidney function improves, the patient takes cyclosporine. Maintenance immunosuppressive therapy usually combines prednisone, azathioprine, and cyclosporine. Patients receiving tacrolimus have less risk of organ rejection and new-onset Type 1 diabetes.

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Nursing Considerations of Hypoglycemia

Review the onset, peak, and duration of action of the insulin your patient uses. When her insulin is at peak effect, check her for signs and symptoms of hypoglycemia. Be familiar with oral antidiabetic drugs that can cause hypoglycemia, such as sulfonylureas. Whether she uses insulin or oral antidiabetic drugs, monitor her blood glucose level before meals and at bedtime and tell her to do the same at home.Advise your patient to administer her insulin and oral antidiabetic drugs on time. Patients should eat 5 to 30 minutes after insulin administration, depending on the type of insulin. For example, a patient should eat within 5 minutes after taking Humalog or 30 minutes after taking regular insulin. If your patient leaves the hospital unit temporarily, make sure she takes her insulin and eats her meals on schedule. If a meal will be delayed, give her a snack. Also, provide betweenmeal and bedtime snacks, if needed, at the time of insulin’s peak activity.

If your patient isn’t allowed anything by mouth before a procedure, contact her physician to obtain changes in orders for her insulin and oral antidiabetic drugs.

Patient Teaching

Teach your patient and her family how to prevent, recognize, and manage hypoglycemia . Making your patient an active participant in her care will help her counter feelings of helplessness and loss of control. Enlist her family’s help and ease their fears by teaching them about hypoglycemia as well.

If your patient experiences hypoglycemia, help her identify what may have caused it. Even mild hypoglycemia will disrupt her daily routine if it occurs frequently. Anticipating hypoglycemia without understanding its causes and treatment may affect her compliance with her regimen. For example, she may be afraid to inject insulin for fear of another hypoglycemic episode.

Assess your patient for administration problems, such as administering too much insulin or too high a dose of an oral antidiabetic drug. Ask her to demonstrate how she administers insulin. Also, discuss the timing, quantity, and content of her meals as well as the extent and timing of exercise.

Encourage your patient to monitor her blood glucose level regularly and whenever she experiences hypoglycemic symptoms. Such monitoring will help her learn her threshold for hypoglycemia and recognize her typical symptoms at various glucose levels. Then when she experiences hypoglycemia, she can treat it appropriately.

Nursing Considerations of HypoglycemiaTeach your patient to recheck her blood glucose level 15 minutes after taking a rapidly absorbed carbohydrate. Encourage her to keep rapidly absorbed carbohydrates, such as hard candies or glucose tablets, available at home and to carry them with her when she goes out. Also, advise the patient to carry a nonperishable snack, such as a package of peanut butter crack­ers, to eat in case a meal isn’t available within 1 hour after a hyperglycemic episode.

Identify a family member or friend who can help your patient if she develops hypoglycemia. Teach this person how to prepare and administer glucagon if hypoglycemia hinders the patient’s ability to swallow. Warn the patient that nausea is a common adverse effect of glucagon; she may need to take small sips of a carbonated, uncaffeinated soft drink until her nausea subsides.

For an elderly patient who lives alone, identify someone who’s willing to learn about hypoglycemia and check on her regularly. Encourage your elderly patient to contact the physician if she experiences frequent hypoglycemia. Also, instruct her to notify the physician if her blood glucose level falls below the target level more often than prescribed guidelines permit. The patient’s drug dosage may need to be adjusted.

Advise your patient to buy a medical alert bracelet or necklace that describes her condition and lists the physician’s phone number-especially if she’s prone to severe hypoglycemia.

When your patient leaves the hospital, give her written discharge instructions about diet, exercise, drugs, blood glucose monitoring, and signs, symptoms, and treatment of hypoglycemia.

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